HMG (Human Menopausal Gonadotropin) – 75 IU

buy hmg peptide, HMG is a dual‑gonadotropin fertility drug that delivers both FSH and LH to directly stimulate sperm production and testosterone output at the testicular level.

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HMG (human menopausal gonadotropin) is a purified biologic containing two human glycoprotein hormones, FSH and LH, each composed of an alpha and beta subunit with essential carbohydrate (glycan) structures that determine stability, receptor binding, and biological activity.

FSH in HMG activates Sertoli cells in the testes, which drives spermatogenesis by supporting germ cell maturation, regulating inhibin B, and maintaining the seminiferous tubule environment. LH activates Leydig cells, stimulating testosterone synthesis through cAMP‑mediated upregulation of steroidogenic enzymes. Together, FSH and LH restore both sides of testicular function: sperm production and intratesticular testosterone.

In clinical use, HMG is employed to treat hypogonadotropic hypogonadism and male infertility because it directly replaces the gonadotropins the pituitary would normally produce. It bypasses the hypothalamus and pituitary entirely, acting directly on the testes to restart endogenous sperm production and testosterone synthesis.